Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Ataxia
ADR ID BADD_A00367
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.02      Gait disturbances
08.01.02.004      Ataxia
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.02      Coordination and balance disturbances
17.02.02.001      Ataxia
Description A disorder characterized by lack of coordination of muscle movements resulting in the impairment or inability to perform voluntary activities. [CTCAE] Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions. [MeSH]
MedDRA Code 10003591
MeSH ID D001259; D001259; D001259
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Ataxia | Ataxia NEC | Ataxic | Ataxic gait | Ataxia aggravated | Dystaxia | Spastic ataxia | Sensory ataxia | Kinetic ataxia | Motor ataxia | Ataxias | Coordination Impairment | Coordination Impairments | Impairment, Coordination | Impairments, Coordination | Dyssynergia | Ataxy | Ataxia, Motor | Ataxias, Motor | Motor Ataxia | Motor Ataxias | Tremor, Rubral | Rubral Tremor | Rubral Tremors | Tremors, Rubral | Ataxia, Truncal | Ataxias, Truncal | Truncal Ataxia | Truncal Ataxias | Dyscoordination | Lack of Coordination | Coordination Lack | Incoordination | Incoordinations | Ataxia, Appendicular | Appendicular Ataxia | Appendicular Ataxias | Ataxias, Appendicular | Ataxia, Limb | Ataxias, Limb | Limb Ataxia | Limb Ataxias | Ataxia, Sensory | Ataxias, Sensory | Sensory Ataxia | Sensory Ataxias
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00464Cidofovir dihydrate--
BADD_D00465Cilazapril monohydrate--
BADD_D00471Ciprofloxacin--
BADD_D00472Ciprofloxacin hydrochloride--
BADD_D00475Citalopram--
BADD_D00476Citalopram hydrobromide--
BADD_D00479Cladribine--
BADD_D00488Clobazam0.001204%
BADD_D00499Clomipramine--
BADD_D00500Clomipramine hydrochloride--
BADD_D00501Clonazepam0.001681%
BADD_D00506Clorazepate dipotassium--
BADD_D00507Clorazepic acid--
BADD_D00511Clozapine--
BADD_D00535Crizotinib--
BADD_D00545Cyclobenzaprine--
BADD_D00546Cyclobenzaprine hydrochloride--
BADD_D00547Cyclopentolate--
BADD_D00548Cyclopentolate hydrochloride--
BADD_D00556Cysteamine--
BADD_D00557Cysteamine bitartrate--
BADD_D00560Cytarabine0.002131%
BADD_D00564Dabigatran etexilate--
BADD_D00574Dalfampridine0.005229%
BADD_D00589Dasatinib--
BADD_D00590Daunorubicin--
BADD_D00591Daunorubicin citrate--
BADD_D00612Desipramine--
BADD_D00613Desipramine hydrochloride--
BADD_D00623Dexamethasone--
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